591.132.1/.2:591.14:636.7:546.133.1 ., , ; ., , ., , ; , . - . : , , , . Naboka L.A., Cand.Vet.Sci, Chubin A.N., Doct.Vet,Sci; Kornilova A.V. post-graduate student, FESAU SECRETORY FUNCTION OF STOMACH OF DOGS AT COMBINED APPLICATION OF ACTIVE SODIUM HYPOCHLORITE AND MEXIDOL In chronic experiments on fistuled dogs the influence of combined application of sodium hypochlorite and mexidol on secretory stomach function was studied. The analysis of results shows the oppressing action on secretion of gastric glands of examined preparations. KEYWORDS: SODIUM HYPOCHLORITE, MEXIDOL, FISTULED DOGS, SECRETORY STOMACH FUNCTION. . , - , , ). , , - , , , [1]. . 12 , 10 – 12 . - , [2]. 2 . - , , - . [5]. , - , , . . . , , 18 - . (38° ) - (10 ) . [3,4]. , - 10 . , (38° ) 500 20 . - 12-15 31 - . - . , ( - , ) , , . – .). - 58% , . - . . . [5], – - t - , 2,8 . . ( - .1), 2,1 . 10 8 6 4 2 0 1 2 3 1 .1. ( 4 2 ) - ( 3 . .). ( ) 8% - . 44%. 1-3%. , ( - - 3%, 3% , . - ) . 32 , ±m 1- % 1,2±0,22 1,9±0,32 158*** , 7,8±1,30 3,6±0,22 28*** % 16,8±,50 24,3±1,32 144*** 82,8±2,61 80,8±2,12 97 % 78,9±2,51 86,0±4,25 108 148,3±6,50 144,6±5,66 97 67,4±4,70 69,2±2,72 % 102 : * <0,05,** <0,01,*** <0,001 58,3±6,71 53,8±1,94 92 + + 2- 3- 5,0±0,41 3,7±0,11 74* , 86,5±3,32 84,8±3,51 98 3,9±0,21 2,9±0,04 74* 72,2±3,10 72,4±1,72 99 132,5±8,31 136,7±4,44 103 112,6±6,42 112,8±2,46 100 66,9±5,13 62,2±1,56 92 69,4±5,91 64,4±2,76 92 , + , - . , - 2%. 8% , - . ( . 2). , 1371,1 2 1516,7 *** 1 2 64% 62% 100% 857,6*** 100% 68% 1 1151,2 1 2 741,9** 64% 12,1** 2333,7 100% 17,7 100% + . 1 , l, , . 2. 1- , 2- : , * <0,05, ** <0,01, *** <0,001 33 2 , . , 1. - , , .- 1997.2. . ., )./ - ( // . 2.- . 5-14. ., ( 32%, - , / 38%, 36%. , , . // : . - ..12.- .112-118 3. . / : . . ,1999.- ., . . 1. – // . – 2001. – .2-12. 4. . 1- . / - . ., . , . . , . . // . – 2003. – . 5. - 3. – . 56-58. ., / . 9 .- .3-12. , . . 2000. 6. , , ) // . – / , // . . – 1960. – 34 4. – .76. . . -